Lorlatinib - API Standards

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Catalogue number:	PA 12 1490000
Chemical name:	Lorlatinib
CAS Number:	1454846-35-5
Category:	pharmaceutical standards,impurities,intermediates,metabolites,Fine Chemicals
Synonyms:	(R)-26-Amino-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile; (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-4,8-methenopyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile;
Molecular form:	C₂₁H₁₉FN₆O₂
Appearance:	White Solid
Mol. Weight:	406.42
Storage:	2-8°C Hygroscopic, Refrigerator, Under inert atmosphere
Shipping Conditions:	Ambient
Applications:	PF- 06463922 is a potent and selective ROS1/ALK inhibitor capable to block crizotinib-resistant ROS1 mutations. Used in the treatment of human cancers.