Name: PBD dimer-2
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 27 0031484
Chemical name:	PBD dimer-2
CAS Number:	145325-57-1
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 8,8′-[1,5-pentanediylbis(oxy)]bis[1,2,3,11a-tetrahydro-7-methoxy-, (11aS,11′aS)-; (11aS,11′aS)-8,8′-[1,5-Pentanediylbis(oxy)]bis[1,2,3,11a-tetrahydro-7-methoxy-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one]; 5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 8,8′-[1,5-pentanediylbis(oxy)]bis[1,2,3,11a-tetrahydro-7-methoxy-, [S-(R,R)]-; (+)-1,1′-[(Pentane-1,5-diyl)dioxy]bis[(11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one]; (11aS,11a'S)-8,8'-(pentane-1,5-diylbis(oxy))bis(7-methoxy-1,2,3,11a-tetrahydro-5H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-5-one);
Molecular form:	C₃₁H₃₆N₄O₆
Appearance:	NA
Mol. Weight:	560.65
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	PBD dimer-2 (compound 2c) is a C8-linked pyrrolobenzodiazepine dimer. PBD dimer-2 can span an extra base pair and cross-link the 5′-Pu-GA(T/A)TC-Py sequence. PBD dimer-2 can be used as a payload for antibody–agent conjugates (ADCs), and it can be used for the research of cancer

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