Forasartan - API Standards

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Catalogue number:	PA 06 2110000
Chemical name:	Forasartan
CAS Number:	145216-43-9
Category:	pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	5-[(3,5-Dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(2H-tetrazol-5-yl)phenyl]pyridine; Pyridine, 5-[(3,5-dibutyl-1H-1,2,4-triazol-1-yl)methyl]-2-[2-(1H-tetrazol-5-yl)phenyl]-;
Molecular form:	C₂₃H₂₈N₈
Appearance:	White to Off-White Solid
Mol. Weight:	416.53
Storage:	2-8°C Hygroscopic, Refrigerator, Under Inert Atmosphere
Shipping Conditions:	Ambient
Applications:	Forasartan, a specific angiotensin II antagonist, is used alone or with other antihypertensive agents to treat hypertension. Forasartan competes with angiotensin II for binding at the AT1 receptor subtype. As angiotensin II is a vasoconstrictor which also stimulates the synthesis and release of aldosterone, blockage of its effects results in a decreases in systemic vascular resistance.