Cyclooctyne-O-NHS ester 

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Catalogue number: PA 27 0031438
Chemical name: Cyclooctyne-O-NHS ester

CAS Number:

1425803-45-7
Category: miscellaneous compounds,Antibody Drug Conjugate
Synonyms:

Acetic acid, 2-(2-cyclooctyn-1-yloxy)-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 2-(2-cyclooctyn-1-yloxy)acetate; 2,5-Dioxopyrrolidin-1-yl 2-(cyclooct-2-ynyloxy)acetate;
Molecular form: C14H17NO5
Appearance: Solid
Mol. Weight: 279.29
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Cyclooctyne-O-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups

Cyclooctyne-O-NHS ester

1425803-45-7
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