Name: Acalabrutinib - API Standards
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 54 50000
Chemical name:	Acalabrutinib
CAS Number:	1420477-60-6
Category:	intermediates,pharmaceutical standards,Fine Chemicals
Synonyms:	4-[8-Amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide; (S)-4-(8-Amino-3-(1-(but-2-ynoyl)pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridin-2-yl)benzamide; (S)-4-[8-Amino-3-[1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-(pyridin-2-yl)benzamide; Calquence;
Molecular form:	C₂₆H₂₃N₇O₂
Appearance:	NA
Mol. Weight:	465.52
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Acalabrutinib is a Bruton tyrosine kinase inhibitor used to treat mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. acalabrutinib has been used in trials studying the treatment of B-All, Myelofibrosis, Ovarian Cancer, Multiple Myeloma, and Hodgkin Lymphoma, among others.This Bruton Tyrosine Kinase (BTK) inhibitor indicated for the treatment of chronic lymphocytic leukemia, small lymphocytic lymphoma, and in adult patients with Mantle Cell Lymphoma (MCL) who have already received at least one prior therapy.

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