DBCO-C6-NHS ester

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Catalogue number:	PA 27 0031405
Chemical name:	DBCO-C6-NHS ester
CAS Number:	1384870-47-6
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	Dibenz[b,f]azocine-5(6H)-hexanoic acid, 11,12-didehydro-ε-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 11,12-didehydro-ε-oxodibenz[b,f]azocine-5(6H)-hexanoate; DBCO-C6NHS;
Molecular form:	C₂₅H₂₂N₂O₅
Appearance:	Solid
Mol. Weight:	430.46
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	DBCO-NHS ester 2 is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 2 is a derivative of Dibenzylcyclooctyne (DBCO) used in copper-free click chemistry[1]. DBCO-NHS ester 2 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups