Vemurafenib-d5

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Catalogue number:	PA STI 086780
Chemical name:	Vemurafenib-d5
CAS Number:	1365986-90-8
Category:	aromatics,heterocycles,protein kinase inhibitors and activators,sulphur and selenium compounds,pharmaceutical standards,intermediates,Fine Chemicals,stable isotopes
Synonyms:	N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide-d5; PLX 4032-d5; RG 7204-d5; Ro 51-85426-d5;
Molecular form:	C₂₃H₁₃D₅ClF₂N₃O₃S
Appearance:	NA
Mol. Weight:	494.95
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Labelled Vemurafeni, a selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600.