Name: Abacavir 5'-Phosphate
Brand: Pharmaffliates
Rating: 4.50 (5 reviews)

Catalogue number:	PA 01 01570
Chemical name:	Abacavir 5'-Phosphate
CAS Number:	136470-77-4
Category:	phosphorylcholine derivatives,drug analogues,metabolites,pharmaceutical standards,amines,aromatics
Synonyms:	(1S,4R)- 4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol Dihydrogen Phosphate (Ester);(1S-cis)-Abacavir Monophosphate; ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methyl dihydrogen Phosphate;
Molecular form:	C₁₄H₁₉N₆O₄P
Appearance:	White Solid
Mol. Weight:	366.31
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

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Abacavir 5'-Phosphate

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