Name: DC41SMe
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 27 0031380
Chemical name:	DC41SMe
CAS Number:	1354787-71-5
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	(S)-N-(2-(1-(chloromethyl)-5-hydroxy-2,3-dihydro-1H-benzo[e]indole-3-carbonyl)-1H-indol-5-yl)-5-(4-methyl-4-(methyldisulfaneyl)pentanamido)-1H-indole-2-carboxamide; 1H-Indole-2-carboxamide, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-5-yl]-5-[[4-methyl-4-(methyldithio)-1-oxopentyl]amino]-; N-[2-[[(1S)-1-(Chloromethyl)-1,2-dihydro-5-hydroxy-3H-benz[e]indol-3-yl]carbonyl]-1H-indol-5-yl]-5-[[4-methyl-4-(methyldithio)-1-oxopentyl]amino]-1H-indole-2-carboxamide;
Molecular form:	C₃₈H₃₆ClN₅O₄S₂
Appearance:	NA
Mol. Weight:	726.31
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	DC41SMe, a DC1 derivative, shows cytotoxicity in Ramos, Namalwa, and HL60/s cells with IC50s ranging from 18-25 pM. DC1, a simplified analogue of CC-1065, is an antibody conjugate of cytotoxic DNA alkylators for the targeted treatment of cancer

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DC41SMe

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