Ribociclib-d6

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Catalogue number:	PA STI 088300
Chemical name:	Ribociclib-d6
CAS Number:	1328934-40-2
Category:	impurities,metabolites,stable isotopes,pharmaceutical standards,Fine Chemicals
Synonyms:	7-Cyclopentyl-N,N-bis(methyl-d3)-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide; Kisqali-d6;7-Cyclopentyl-N,N-di(methyl-d3)-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide;
Molecular form:	C₂₃H₂₄D₆N₈O
Appearance:	NA
Mol. Weight:	440.58
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	LEE011-d6 is the isotope analog of LEE011. LEE011 is an orally bioavailable and highly specific CDK4/6 (cyclin-dependent kinase 4/6) inhibitor. LEE011 in combination with LGX818 leads to robust anti-tumor activity in melanoma and breast cancer tumor models.