Name: TH1338
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 03 0061014
Chemical name:	TH1338
CAS Number:	1258494-60-8
Category:	chiral standards,heterocycles,enzyme inhibitors,pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate
Synonyms:	1H-Pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 5-amino-4,11-diethyl-4-hydroxy-, (4S)-; (4S)-5-Amino-4,11-diethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (S)-5-amino-4,11-diethyl-4-hydroxy-1,12-dihydro-14H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H)-dione;
Molecular form:	C₂₂H₂₁N₃O₄
Appearance:	Solid
Mol. Weight:	391.43
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	TH1338 (compound 3b), an orally active camptothecin derivative and a potent chemotherapeutic agent for cancer, demonstrates excellent cytotoxic potency against human tumor cell lines in vitro. TH1338 (compound 3b) possesses significant brain penetration, favorable efflux pump properties, and hematological toxicity profile

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TH1338

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