DBCO-PEG4 amine

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Catalogue number: PA 27 0030861
Chemical name: DBCO-PEG4 amine

CAS Number:

1255942-08-5
Category: miscellaneous compounds,Antibody Drug Conjugate
Synonyms:

4,7,10,13-Tetraoxapentadecanamide, 15-amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-; 15-Amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-4,7,10,13-tetraoxapentadecanamide; ADIBO-PEG4-amine;
Molecular form: C29H37N3O6
Appearance: NA
Mol. Weight: 523.63
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB−MMAE and DBCO-TRX−MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)

DBCO-PEG4 amine

1255942-08-5
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