Name: Abacavir Sulfate - Impurity C (Freebase)
Brand: Pharmaffliates
Rating: 4.50 (5 reviews)

Catalogue number:	PA 01 01510
Chemical name:	[(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-en-1- yl]methanol
CAS Number:	124752-25-6
Similar Products:	138233-46-2(HCl Salt)
Category:	intermediates,pharmaceutical standards,Fine Chemicals,bases and related reagents,nucleotides
Synonyms:	(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentene-1-methanol; ((1S,4R)-4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol; Descyclopropyl Abacavir; [(1S,4R)-4-(2,6-Diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol (USP);
Molecular form:	C₁₁H₁₄N₆O
Appearance:	Off-White to Pale Yellow Solid
Mol. Weight:	246.27
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

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Abacavir Sulfate - Impurity C (Freebase)

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