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Catalogue number: PA STI 074230
Chemical name: Plerixafor-d4

CAS Number:

1246819-87-3

Category: aromatics,heterocycles,enzyme inhibitors,stable isotopes,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:

1,1'-[1,4-Phenylenebis(methylene)]bis[4,8,11-tris(trifluoroacetyl)-1,4,8,11-tetraazacyclotetradecane-d4;

Molecular form: C28H50D4N8
Appearance: Off-White Solid
Mol. Weight: 506.81
Storage: 2-8°C Hygroscopic, Refrigerator, Under Inert Atmosphere
Shipping Conditions: Ambient
Applications: Labelled Plerixafor, it is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM).

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