Tosedostat-d5

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Catalogue number:	PA STI 083980
Chemical name:	Tosedostat-d5
CAS Number:	1217844-03-5
Category:	stable isotopes,miscellaneous compounds
Synonyms:	(αS)-α-[[(2R)-2-[(1S)-1-Hydroxy-2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]amino]benzeneacetic Acid-d5 Cyclopentyl Ester; CHR 2797-d5;
Molecular form:	C₂₁H₂₅D₅N₂O₆
Appearance:	NA
Mol. Weight:	411.50
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Labelled Tosedostat. CHR-2797 is a novel metalloenzyme inhibitor that is converted into a pharmacological active acid product inside cells. CHR-2797 exerts antiproliferative effects against a range of tumor cell lines in vitro and in vivo and shows selectivity for transformed over nontransformed cells. Its antiproliferative effects are at least 300 times more potent than the prototypical aminopeptidase inhibitor, Bestatin.

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