Colchicine Methanethiosulfonate

In House Impurity

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Catalogue number:	PA 03 0741001
Chemical name:	Colchicine Methanethiosulfonate
CAS Number:	1217821-52-7
Category:	chiral standards,enzyme inhibitors,enzyme activators,sulphur and selenium compounds,pharmaceutical standards,impurities,metabolites,Fine Chemicals
Synonyms:	(S)-S-(3-oxo-3-((1,2,3,10-Tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)amino)propyl) methanesulfonothioate;
Molecular form:	C₂₄H₂₉NO₈S₂
Appearance:	Pale Yellow to Light Yellow Solid
Mol. Weight:	523.62
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	The methanethiosulfonate derfivative of Colchicine, an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.