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Catalogue number: PA 27 0030838
Chemical name: Azido-PEG8-NHS ester

CAS Number:

1204834-00-3

Category: miscellaneous compounds,Antibody Drug Conjugate
Synonyms:

Propanoic acid, 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[(23-azido-3,6,9,12,15,18,21-heptaoxatricos-1-yl)oxy]propanoate; Azido-dPEG8-NHS ester;

Molecular form: C23H40N4O12
Appearance: Liquid
Mol. Weight: 564.59
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Azido-PEG8-NHS ester is a cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azido-PEG8-NHS ester is also a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[2]. Azido-PEG8-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups

Azido-PEG8-NHS ester

1204834-00-3
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