Spebrutinib - API Standards

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Catalogue number:	PA 19 1730000
Chemical name:	Spebrutinib
CAS Number:	1202757-89-8
Category:	enzyme activators,enzyme inhibitors,impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	AVL-292; N-(3-((5-Fluoro-2-((4-(2-methoxyethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide;
Molecular form:	C₂₂H₂₂FN₅O₃
Appearance:	NA
Mol. Weight:	423.45
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	AVL-292 is a potent and specific Bruton's tyrosine kinase (Btk) inhibitor. Studies showed that AVL-292 used in combination with Carfilzomib impacted the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.