6-Methylthioguanine

In House Impurity

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Catalogue number:	PA 01 0241015
Chemical name:	6-Methylthioguanine
CAS Number:	1198-47-6
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	6-(Methylthio)-7H-purin-2-amine; 1H-Purin-2-amine, 6-(methylthio); 6-(Methylthio)-9H-purin-2-amine; Purine, 2-amino-6-(methylthio); S-Methyl-6-thioguanine;
Molecular form:	C₆H₇N₅S
Appearance:	White to Off-White Solid
Mol. Weight:	181.22
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	A metabolite of 2’-Deoxy-6-thio Guanosine (D281650) and 6-Thioguanine. An effective immunosuppressant and anticancer agent, however chronic exposure can be mutagenic in human cells as long-term use of thiopurines was found to be associated with a significantly increased risk of various types of cancer.