1-(3-Chlorophenyl)piperazine-d8

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Catalogue number:	PA STI 020590
Chemical name:	1-(3-Chlorophenyl)piperazine-d8
CAS Number:	1189923-43-0
Category:	metabolites,impurities,pharmaceutical standards,intermediates,Fine Chemicals,stable isotopes
Synonyms:	1-(m-Chlorophenyl)piperazine-d8; 4-(3-Chlorophenyl)piperazine-d8; N-(3-Chlorophenyl)piperazine-d8; N-(m-Chlorophenyl)piperazine-d8; NSC 49307-d8; mCPP-d8;
Molecular form:	C₁₀H₅D₈ClN₂
Appearance:	Sticky Yellow Oil
Mol. Weight:	204.73
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	It is noteworthy that 1-(3-Chlorphenyl)piperazine (m-CPP), resulting from N-dealkylation of Trazodone, is a major circulating metabolite in humans common to several antidepressants including Trazodone, Nefazodone, and Etoperidone. The metabolite m-CPP is of significant interest because it has 5-HT2C agonistic and 5-HT2A antagonistic properties. It has also been suggested that m-CPP may contribute to the antidepressant efficacy of Trazodone.