PF 184

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Catalogue number: PA 27 0021208
Chemical name: PF 184

CAS Number:

1187460-81-6
Category: miscellaneous compounds
Synonyms:

8-(2-((3S,4R)-3,4-Bis(hydroxymethyl)-3,4-dimethylpyrrolidin-1-yl)-5-chloroisonicotinamido)-1-(4-fluorophenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide;
Molecular form: C32H32ClFN6O4
Appearance: NA
Mol. Weight: 619.09
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress.

PF 184

1187460-81-6
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