Name: Duocarmycin A
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 04 3160000
Chemical name:	Duocarmycin A
CAS Number:	118292-34-5
Category:	Fine Chemicals,pharmaceutical standards,intermediates,Antibody Drug Conjugate
Synonyms:	Cyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylic acid, 1,2,4,5,6,7,8,8a-octahydro-6-methyl-4,7-dioxo-2-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]-, methyl ester, (6R,7bR,8aS)-; Methyl (6R,7bR,8aS)-1,2,4,5,6,7,8,8a-octahydro-6-methyl-4,7-dioxo-2-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]cyclopropa[c]pyrrolo[3,2-e]indole-6-carboxylate; (+)-Duocarmycin A; DC 88A;
Molecular form:	C₂₆H₂₅N₃O₈
Appearance:	NA
Mol. Weight:	507.5
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC-2 cells typically apoptotic changes, including chromatin condensation, sub-G1 accumulation in DNA histogram pattern, and decrease in procaspase-3 and 9 levels

Enquire for Duocarmycin A

Duocarmycin A

CAS Number: