(R)-(+)-Blebbistatin

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Catalogue number:	PA 27 0021140
Chemical name:	(R)-(+)-Blebbistatin
CAS Number:	1177356-70-5
Category:	miscellaneous compounds
Synonyms:	(R)-3a-Hydroxy-6-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one;
Molecular form:	C₁₈H₁₆N₂O₂
Appearance:	Yellow Solid
Mol. Weight:	292.34
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	(R)-(+)-Blebbistatin is a 1-phenyl-2-pyrrolidinone derivative and a selective inhibitor of non-muscle myosin II (1, 2, 3). It blocks cell blebbing rapidly and reversibly and also disrupts directed cell migration and cytokinesis in vertebrate cell. (R)-(+)-Blebbistatin can also inhibit contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. (R)-(+)-Blebbistatin is suitable as a negative control for (S)-(-)-Blebblastatin.