Clemizole Hydrochloride - API Standards

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Catalogue number:	PA 03 3670000
Chemical name:	Clemizole Hydrochloride
CAS Number:	1163-36-6
Alternate CAS Number:	Free Base 442-52-4
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	1-[(4-Chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole;hydrochloride;
Molecular form:	C₁₉H₂₁Cl₂N₃
Appearance:	White to Off-White Solid
Mol. Weight:	362.3
Storage:	2-8°C Hygroscopic, Refrigerator, Under Inert Atmosphere
Shipping Conditions:	Ambient
Applications:	Clemizole Hydrochloride inhibits Hepatitis C RNA replication in cell culture through the suppression of the binding between the nonstructural protein 4B and the viral RNA genome with little toxicity for the host cell. Clemizole Hydrochloride is also a potent inhibitor of transient receptor potential channel TRPC5.