Debrisoquine - API Standards

Stock Status : <%stockStatus%>

<%deliveryStatus%>

Catalogue number:	PA 04 2780000
Chemical name:	Debrisoquine
CAS Number:	1131-64-2
Category:	impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	2(1H)-Isoquinolinecarboxamidine, 3,4-dihydro; 3,4-Dihydro-2(1H)-isoquinolinecarboximidamide; 1,2,3,4-Tetrahydroisoquinoline-2-carboximidamide; 2-Amidino-1,2,3,4-tetrahydroisoquinoline; 3,4-Dihydroisoquinoline-2(1H)-carboximidamide;
Molecular form:	C₁₀H₁₃N₃
Appearance:	NA
Mol. Weight:	175.24
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	An adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.