Amitriptyline N-β-D-Glucuronide

In House Impurity

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Catalogue number:	PA 01 0941000
Chemical name:	Amitriptyline N-β-D-Glucuronide
CAS Number:	112806-33-4
Category:	intermediates,impurities,metabolites,pharmaceutical standards,Fine Chemicals,glucuronides
Synonyms:	(2S,3S,4S,5R,6R)-6-[Dimethyl-[3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propyl]azaniumyl]-3,4,5-trihydroxyoxane-2-carboxylate;
Molecular form:	C₂₆H₃₁NO₆
Appearance:	NA
Mol. Weight:	453.54
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Amitriptyline N--D-Glucuronide is used in biological studies for biphasic kinetics of quaternary ammonium glucuronide formation from amitriptyline and diphenhydramine in human liver microsomes. Also, this compound is used in analytical studies to detect amitriptyline and diphenhydramine N-glucuronides in human urine using HPLC with and without hydrolysis.