MCOPPB Trihydrochloride

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Catalogue number:	PA 27 0020423
Chemical name:	MCOPPB Trihydrochloride
CAS Number:	1108147-88-1
Alternate CAS Number:	freeamine: 1028969-49-4
Category:	miscellaneous compounds
Synonyms:	1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-(3R)-3-piperidinyl-1H-benzimidazole TriHydrochloride;
Molecular form:	C₂₆H₄₃Cl₃N₄
Appearance:	White Solid
Mol. Weight:	518.01
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	A potent non-peptide nociceptin/orphanin FQ peptide (NOP)-receptor full agonist [or opioid-receptor-like-1 (ORL1) receptor agonist]. It is the most potent, non-peptide NOP full agonists in vitro and a potent anxiolytic in the mice. It inhibited signaling through the NOP receptor in the mouse brain, suggesting that it penetrated into the brain after it was orally administered. It did not affect locomotor activity or memory, nor did it contribute to ethanol-induced hypnosis.