Triethylene Glycol 2-Bromoethyl Methyl Ether

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Catalogue number:	PA 27 0030808
Chemical name:	Triethylene Glycol 2-Bromoethyl Methyl Ether
CAS Number:	110429-45-3
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	2,5,8,11-Tetraoxatridecane, 13-bromo-; 13-Bromo-2,5,8,11-tetraoxatridecane; 1-[2-[2-(2-Bromoethoxy)ethoxy]ethoxy]-2-methoxyethane; 1-Bromo-3,6,9,12-tetraoxatridecane; 2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethyl bromide; Triethylene glycol mono(2-bromoethyl) ether methyl ether;
Molecular form:	C₉H₁₉BrO₄
Appearance:	Liquid
Mol. Weight:	271.15
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency[1]. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs.