Linopirdine

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Catalogue number: PA 12 1540000
Chemical name: Linopirdine

CAS Number:

105431-72-9
Category: impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:

1-Phenyl-3,3-bis(pyridin-4-ylmethyl)-1,3-dihydro-2H-indol-2-one; 1-Phenyl-3,3-bis(pyridin-4-ylmethyl)indol-2-one;

Molecular form: C26H21N3O
Appearance: NA
Mol. Weight: 391.47
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Linopirdine is a putative cognition-enhancing drug with a novel mechanism of action. Linopirdine blocks the KCNQ2\3 heteromer M current with an IC50 of 2.4 micromolar disinhibiting acetylcholine release, and increasing hippocampal CA3-schaffer collateral mediated glutamate release onto CA1 pyramidal neurons.

Linopirdine

105431-72-9
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