Name: Iloprost-d4 (Major)
Brand: Pharmaffliates
Rating: 4.50 (5 reviews)

Catalogue number:	PA STI 052660
Chemical name:	Iloprost-d4 (Major)
CAS Number:	1035094-10-0
Category:	chiral standards,enzyme inhibitors,stable isotopes,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic Acid-d4; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane-d4; Ciloprost-d4; Endoprost-d4; Ilomedin-d4; ZK 36374-d4;
Molecular form:	C₂₂H₂₈D₄O₄
Appearance:	Pale Yellow Oil
Mol. Weight:	364.51
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	A labelled synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time.

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