MK-2206 Dihydrochloride

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Catalogue number:	PA 27 0017909
Chemical name:	MK-2206 Dihydrochloride
CAS Number:	1032350-13-2
Category:	miscellaneous compounds
Synonyms:	8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride; 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one;dihydrochloride;
Molecular form:	C₂₅H₂₃Cl₂N₅O
Appearance:	Yellow Solid
Mol. Weight:	480.39
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	AZD 6244 and MK 2206 are targeted small-molecule drugs that inhibit MEK and AKT responses. The combination of AZD6244 and MK2206 has a significant synergistic effect on tumor growth in vitro and in vivo and leads to increased survival rates in mice bearing highly aggressive human lung tumors. Antitumor agents. Potent AKT inhibitor.