(2R,4R)-1-Boc-N-Fmoc-4-amino-pyrrolidine-2-carboxylic Acid

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Catalogue number:	PA 27 0015285
Chemical name:	(2R,4R)-1-Boc-N-Fmoc-4-amino-pyrrolidine-2-carboxylic Acid
CAS Number:	1018332-24-5
Category:	miscellaneous compounds
Synonyms:	n-boc-cis-4-n-fmoc-amino-d-proline; (2r,4r)-4-((((9h-fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid;
Molecular form:	C₂₅H₂₈N₂O₆
Appearance:	NA
Mol. Weight:	452.51
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	(2R,4R)-1-Boc-N-Fmoc-4-amino-pyrrolidine-2-carboxylic Acid can be used as reactant/reagent in synthetic preparation of KMI-008 peptide derivatives and proline-based peptidomimetic analogs and determination of their activity as BACE1 inhibitors (β-secretase inhibitors). It can also be used as reagent/reactant for preparation of aminoproline residues for solid phase synthesis of integrin binding cyclic peptides by bromination, azidation and protection/deprotection protocol.