Methyl N-[[4-[(2-amino-5-phenylphenyl)carbamoyl]phenyl]methyl]carbamate

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Catalogue number:	PA 27 0017098
Chemical name:	Methyl N-[[4-[(2-amino-5-phenylphenyl)carbamoyl]phenyl]methyl]carbamate
CAS Number:	1013330-79-4
Category:	miscellaneous compounds
Synonyms:	N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester;
Molecular form:	C₂₂H₂₁N₃O₃
Appearance:	NA
Mol. Weight:	375.43
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester is a biaryl benzamides that exhibit inhibitory selectivity over class II Histone Deacetylase (HDACs) and as well as class I HDACs. N-[[4-[[(4-Amino[1,1'-biphenyl]-3-yl)amino]carbonyl]phenyl]methyl]carbamic Acid Methyl Ester was deteremined to be a potent and selective inhibitor of HDAC with reduced off-target activity and tumor growth inhibition activity.