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Catalogue number: PA 27 0016671
Chemical name: SMAD3 Inhibtor, SIS 3

CAS Number:

1009104-85-1

Category: miscellaneous compounds
Synonyms:

1-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one;

Molecular form: C28H27N3O3
Appearance: NA
Mol. Weight: 453.54
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: SMAD3 Inhibitor, SIS3 selectively inhibits TGF-B and activin. It has been shown to reduce TGF-B1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts.

SMAD3 Inhibtor, SIS 3

1009104-85-1
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